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Welcome to the MateraLab at UNC Chapel Hill!

At a Glance

  • Epigenetic gene regulation (current)
    • Cellular decision making and memory
    • RNA processing events at the chromatin interface
  • Ribonucleoprotein (RNP) assembly and transport (previous)

The research in our laboratory centers on fundamental mechanisms that regulate eukaryotic gene expression. In particular, we are interested in the roles played by histone post-translational modifications (PTMs) in the transmission of genetic and epigenetic information that is required for proper metazoan development and genome function. These studies are expected to provide foundational knowledge important for understanding disease mechanisms in different types of cancer and other human disorders.

A deeper, and somewhat more personal, perspective on the field of RNA biology and RNP research can be found here: Twenty Years of RNA.

 

Affiliations

Dept. of Biology.  Dept. of Genetics.  iBGS Program.  Lineberger Cancer Center.

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Drosophila and human body plan images courtesy of droso4schools.com.