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MateraLab Projects

Epigenetics (main focus)  

Regulation of Gene Expression

  • Role of histone PTMs in transcription and RNA processing
  • Understanding contribution of histone PTMs to cellular memory
  • Developing new tools to study multi-copy gene families
  • Supported by NIH grant R35-GM136435 (renewed Jun 2025)

SMN Function (secondary focus)

Spinal Muscular Atrophy

  • Biophysical methods to understand SMN oligomerization
  • Supported by UNC RIDE award