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MateraLab Projects

Epigenetics (Regulation of Gene Expression)  

  • Role of histone PTMs in transcription and RNA processing
  • Understanding contribution of histone PTMs to cellular memory
  • Developing new tools to study multi-copy gene families
  • Supported by NIH grant R35-GM136435

SMA (Spinal Muscular Atrophy)

  • Function of the SMN complex in snRNP biogenesis
  • Use of animal models to understand disease etiology
  • Identification of novel functions of SMN complex
  • Supported by NIH grant R35-GM136435